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ALPHA-1 ANTITRYPSIN DEFICIENCY (ALPHA-1)

Uncover Alpha‑1. Understand what’s next.

Alpha‑1 is a genetic condition that can damage the lungs—

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but there’s a test your doctor can do to see if you’re at risk.

Find out how

Up to 30% of people with COPD (chronic obstructive pulmonary disease) or asthma may have an underlying genetic cause, such as Alpha‑1, for their lung disease.

Take a closer look at Alpha‑1

Alpha‑1 can result in serious lung disease in adults. It also may result in liver disease at any age. Whether Alpha‑1 may affect the lungs, the liver, or both depends on the combination of Alpha‑1 genes someone has and other risk factors. The Alpha‑1 Basics page has more details about Alpha‑1 genetics and what symptoms may be associated with this rare disorder.

Watch the video below to learn more about what happens in the body of someone with Alpha‑1.

Video thumbnail of lungs with body.

Discover more about Alpha‑1

Husband and wife talking about management options for Alpha-1.

If you have Alpha‑1, be sure to talk to your doctor about this condition and options to help manage it.

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Explore helpful resources and get tips for living with Alpha‑1.

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Reviewed by Takeda MARCH 2022.